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                   5-HT?/span>5-Hydroxytryptamine?span lang="EN-US">5-羟色胺)神经Ψһ递质主要分布于松果体和下丘脑,可参与食欲、体温调节,情绪 心血管功能,内分泌和抑郁等生理塿能的调节?span lang="EN-US">5-HT通过激动不同的5-HT受体,可具有不同药理作攨,因此,5-HT受体拮抗剂Home为药物设计的研究热点[1][2]。百灵威作为专业试剂供应啡,提供多种5-HT受体拮抗剂,丨您的科研助力加ٷ油!

                • 质量稳定Hv性价比高
                • 现货供应,发ǡ货及?/strong>            

                产品编号

                中英文名?/span>

                CAS

                规格

                384285

                Granisetron hydrochloride, 98%, a serotonin 5-HT3 receptor antagonist

                盐酸格 ҳ司琼, 98%, 5-HT3受体拮抗?/span>

                107007-99-8

                200 mg

                1 g

                283801

                Ketanserin, 99%, a specific 5-HT2A serotonin receptor antagonist

                凯他色林, 99%, 特异性的5-HT2A 5-羟色胺受体拮抗剂

                74050-98-9

                250 mg

                1 g

                185928

                Lamotrigine, 98%, Novel anticonvulsant drug for inhibition of 5-HT

                拉莫三嗪, 98%, 抑制5-羟色?/span>(5-HT)吸收

                84057-84-1

                1 g

                5 g

                574335

                Mirtazapine, 99%, 5-HT Receptor

                米尔塔扎2019ٷ?/span>, 99%, 5-HT叡体抑制?/span>

                85650-52-8

                100 mg

                496697

                Olanzapine, 99%, High affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist

                奥氮?/span>, 99%, 5-HT2?/span>D2受L高亲和性拮抗剂

                132539-06-1

                1 g

                5 g

                977215

                Paliperidone, 99%, potent D2 and 5-HT2A antagonist

                帕潘立酮, 99%, 高效D2?/span>5HT2A拮抗?/span>

                144598-75-4

                10 mg

                50 mg

                144809

                Sumatriptan succinate, 98%, 5-HT1 receptor agonist

                琥珀酸舒马曲普坦, 98%, 5-HT1 受体激动剂

                103628-48-4

                100 mg

                500 mg

                522188

                Tropisetron monohydrochloride, 99%, 5-HT3 receptor antagonist and α7-nicotinic receptor agonist

                盐酸托烷司琼, 99%, 5-HT3受体拮抗剂和α7-烟碱受体激动剂

                105826-92-4

                1 g

                5 g

                186095

                Ziprasidone hydrochloride monohydrate, 99%, a novel and potent dopamine and serotonin (5-HT) receptor antagonist

                齐⋉西酮盐酸盐一水合?/span>, 99%, 有效?/span>dopamine ?/span> serotonin (5-HT) receptor的拮抗ǹٷ

                138982-67-9

                250 mg

                1 g

                                 

                                                       Figure1                                                                                      Figure2

                Figure1: Structure of Lamotrigine (185928)[1] 

                Figure2: Interactions of Lamotrigine(185928) with the binding pocket (subdomain IB)[1]

                 References

                [1] Poureshghi F, Ghandforoushan P, Safarnejad A, et al. Interaction of an antiepileptic drug, lamotrigine with human serum albumin (HSA): Application of spectroscopic techniques and molecular modeling methods[J]. Journal of Photochemistry and Photobiology B: Biology, 2017, 166: 187-192.

                [2]Yatham L N, Beaulieu S, Schaffer A, et al. Optimal duration of risperidone or olanzapine adjunctive therapy to mood stabilizer following remission of a manic episode: A CANMAT randomized double-blind trial[J]. Molecular psychiatry, 2016, 21(8): 1050-1056.

                 

                产品编号

                中英文名?/span>

                CAS

                包装规格

                163651

                (+)-Bicuculline, 99.5%, GABAA antagonist

                (+)-荷包牡丹?/span>, 99.5%, GABAA 拮抗?/span>

                485-49-4

                25 mg

                100 mg

                240627

                Candesartan cilexetil, 98%, ATR antagonist

                坎地沙坦?/span>, 98%, ATR 拮抗?/span>

                145040-37-5

                50 mg

                100 mg

                500 mg

                410760

                Cyproterone acetate, 98%, an androgen receptor (AR) antagonist

                环丙孕酮醋酸?/span>, 98%, 一种雄激紡ޠ受体拮抗剂

                427-51-0

                50 mg

                250 mg

                1 g

                195685

                Leuprorelin acetate, 98%, an agonist at pituitary GnRH receptors

                醋酸亮丙瑞林, 98%, 一种垂体促Home性腺激素受体抑制剂

                74381-53-6

                5 mg

                25 mg

                408413

                Tropicamide, 99%, potent selective M4 antagonist

                托品酰胺, 99%, 有效选?/span>M4拮抗?/span>

                1508-75-4

                10 g

                ?nbsp;相关产品?/strong>

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                 蛋白酶体ô制?/span>

                百灵威新型生?/span>
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                百灵威核心生化试?/span>

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                ??/span> 总共1?/span>